This panel of cell lines is useful for studying breast cancer, breast cancer metastasis, mouse models of breast cancer, oncogenes in cell transformation, EGFR-MEK signaling pathways, as well as anti-cancer drug discovery and drug resistance.
Biosafety Level
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Comments
The Breast Cancer Mouse Model Cell Line Panel is composed of eight immortalized mouse mammary epithelial cell lines that stably overexpress MEK1 activated mutant (MEKDD), EGFR2/Neu, Myc or Ha-Ras.